Abstract: The large size direct coupling technology was studied by coupling a 40 mm diameter image intensifier with a full-frame CMOS. To solve the problems of large-size ICCD/ICMOS made by lens coupling, such as large volume, large light energy loss, and large number of moiré fringes in optical cone coupling devices, a direct coupling process is proposed to make ICCD/ICMOS. The large-size ICMOS developed in this study can obtain more information in the field of view. The resolution of the entire device is up to 3600×1800, the picture is clear, there is no obvious moiré fringe, and the structure is compact. The entire device has the size of a handheld digital camera and has strong concealability, which is conducive to obtaining target information more accurately and quickly in a complex environment.