Abstract: Photomultiplier tubes(PMTs) are sensitive photodetectors used widely in numerous fields. To ensure the long-term stability of the PMT, the material should be carefully selected. As the cable jacket material is in contact with the liquid medium for extended periods, its compatibility with the liquid considerably affects the detection efficiency of the PMT. Therefore, the selection of the cable jacket material is of great significance. In this study, the variation in the transmittance of liquid samples after immersion in different jacket materials was measured using a spectrophotometer. The compatibility of four types of jacket materials(PFA, HDPE, FEP, and PTFE) with three liquids (pure water, oil, and liquid scintillator) was studied. The results show that the four types of jacket materials have good compatibility with water and oil but relatively poor compatibility with the liquid scintillator. Among these, PFA and FEP exhibited the best compatibility.